Are there rules that make a tiny creature harder to hit the farther away it is?

@JeremyECrawford @ChrisPerkinsDnD are there rules that make a tiny creature (hummingbird size) harder to hit the farther away it is?

— shnelle hope (@shnellehope) April 10, 2017

Everything is harder to hit the farther away it is. The rules account for this by imposing disadvantage on long-range attacks. #WOTCstaff https://t.co/KGahE90RsO

— Christopher Perkins (@ChrisPerkinsDnD) April 10, 2017

@ChrisPerkinsDnD On that note – Is there any penalty for a huge creature attempting to hit a diminutive creature? Or would this be handled in AC already?

— Lucas Cordina (@LucasCordina) April 10, 2017

It's handled by the target's AC. Dexterity and armor, not size, is key. Tiny creatures can be easy to hit (e.g., a slug). #WOTCstaff https://t.co/Onegm52Drp

— Christopher Perkins (@ChrisPerkinsDnD) April 10, 2017